![]() Naturally-occurring hyperadrenocorticismĬortisol is a hormone produced in the body by the adrenal glands two small glands situated just in front of the kidneys. If high doses of these drugs are used over a long period of time, they will have the same effect as occurs with naturally-occurring hyperadrenocorticism. These drugs can be corticosteroids (often used to manage inflammation or allergies), but in cats progesterone-type drugs (progestagens) that are sometimes used to control reproductive cycling in entire female cats also have potent cortisol-like actions. Iatrogenic hyperadrenocorticism is the term used to refer to the disease when it is induced by the long-term administration of high doses of cortisol-like drugs. What causes hyperadrenocorticism? Iatrogenic hyperadrenocorticism Hyperadrenocorticism can also be induced by using high doses of cortisol-like hormones over a long period of time, as is sometimes necessary to control some diseases. The excessive cortisol concentrations can cause a variety of abnormalities including excessive thirst, weakness and skin changes. This disease is much more common in dogs than it is in cats, and is generally more difficult to control in cats than it is in dogs, although successful treatment is possible. In some cases it will be due to an abnormality of the adrenal glands themselves.Ĭat showing wounds as a result of thin and fragile skin – a sign of Cushing’s disease ![]() This is most often caused by an abnormality of the pituitary gland (located at the base of the brain) which controls production of the adrenal gland hormones, along with many others. ![]() It is an uncommon disease in cats that develops when there is a persistent excessive production of the hormone cortisol from the adrenal glands (located close to the kidneys in the abdomen). Hyperadrenocorticism is also known as Cushing’s disease or Cushing’s syndrome. ![]()
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